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This discovery unveils a novel mechanism of P53 in tumor suppressionbeyond its conventional roles in cell cycle control and apoptosis induction, P53 can also exert antitumor effects by modulating cellular metabolic pathways
Elevated levels of activating transcription factor 3 (ATF3), p53, and Baxa gene targeted by p53were detected in the gut tissues of individuals with CD, where the ATF3 controls cell death via p53 [34]
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Biochim Biophys Acta 1647(12):361366 Simon E, Vogel M, Fingerhut R, Ristoff E, Mayatepek E, Spiekerkotter U (2009) Diagnosis of glutathione synthetase deficiency in newborn screening
Safety Considerations By Administration Route Glutathione is generally safe
