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2019;76(2):211216., [4] Brggemann N, Heldmann M, Klein C, et al

The Occurrence of Hyperactivated Platelets and Fibrinaloid Microclots in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) Pharmaceuticals

It is known that Down patients suffer from mild to moderate oxidative stress due to the overexpression of the Cu-Zn superoxide dismutase (SOD) gene that is also located on chromosome 21 [62]

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Pyruvate could also be converted to oxaloacetate by pyruvate carboxylase (MSMEG_2412) (unique

Lysates were clarified by centrifugation (20,000 g , 15 min) and protein concentration was determined (BCA protein assay Kit, Pierce, Thermo scientific, IL, USA)
