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Tracey TJ, Steyn FJ, Wolvetang EJ, Ngo ST (2018) Neuronal lipid metabolism: multiple pathways driving functional outcomes in health and disease

Transcutaneous Electrical Nerve Stimulation (TENS): Could alleviate pain by providing mild electrical impulses to nerves

However, CS-917 exhibited good tolerability and safety in overnight-fasted healthy volunteers (in phase 1 clinical trials) and patients with T2DM (in phase 2 clinical trials)

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It plays a critical role in energy production by increasing the availability of ATP (adenosine triphosphate), the primary energy molecule

To establish a robust mechanistic frameworkparticularly concerning mitochondrial bioenergetics and redox homeostasis, highly relevant in vivo and in vitro preclinical models were also deemed eligible for inclusion