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A wide range of TCM-derived compounds have been studied for their neuroprotective effects in AD (Zhang et al., 2015)
If successful in these organisms, candidate compounds of interest may then be studied in mammalian models

High homocysteine levels are associated with vascular damage, neuroinflammation, and synaptic dysfunction, all of which contribute to cognitive decline [36]
Involvement of mitochondrial apoptosis pathway

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Kunkel EJ, Butcher EC
