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[] In addition, FGF21 derived from the liver and/or adipocytes can induce adiponectin (a classical adipokine, which can reduce hepatic gluconeogenesis and steatosis [,,,,,,] ) expression in adipocytes through binding to a heteromeric membrane receptor tyrosine kinase complex composed of a conventional FGF receptor and co-receptor -Klotho

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At present, limited research has been conducted on the therapeutic effect of H 2 in treating intestinal I/R injury, and the underlying mechanisms are summarized below (Table 3)

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