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Observed findings depend on route, formulation, concentration, and study design

10.1016/j.ejphar.2014.01.046 [DOI] [PubMed] [Google Scholar] Associated Data This section collects any data citations, data availability statements, or supplementary materials included in this article
RANKL, which is produced by osteoblasts, osteocytes, bone marrow stromal cells, and activated T and B lymphocytes, binds to RANK on osteoclast precursors to promote their differentiation into mature osteoclasts and to enhance osteoclastic activity via NF-B signaling

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