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Specifically, it participates in the conversion of branched-chain amino acids (BCAAs) valine, leucine, and isoleucine into their keto analogs, a crucial function during fasting and exercise

Shortly, Vitamin B 1 (thiamin) is required in the citric acid cycle for the oxidative decarboxylation of the multi-enzyme branched-chain ketoacid dehydrogenase complexes

Another study has confirmed that the ablation of Insr specifically in adipocytes using the Adipoq-Cre system does not affect the development of BMAds, but instead decreases their size (399), identifying a conserved function of insulin signaling in at least basal BMAd lipogenesis

doi: 10.1016/j.lfs.2010.05.019

Revisiting glutamate excitotoxicity in amyotrophic lateral sclerosis and age-related neurodegeneration

It utilizes the natural compound L-Carnitine to support the transportation of fatty acids to the mitochondria, where they can be burned off as energy