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Fatty acid oxidation organizes mitochondrial supercomplexes to sustain astrocytic ROS and cognition
PPAR- agonists prevent tubule cell death and intracellular lipid accumulation

doi: 10.1097/00002826-199312000-00007

Therefore, a prerequisite for CV is having a high estrogen level

Wen X, Zhang B, Wu B, et al

That seal might not hold up at high temperatures