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Amylin Receptors (Brain): Satiety and Appetite Amylin receptors are concentrated in brain regions that handle fullness signals, including the area postrema and hypothalamus
Pregnant women at greatest risk for deficiency include vegans and vegetarians, those with autoimmune pernicious anaemia or malabsorption syndromes such as Crohns disease (an inflammatory intestinal disease) or coeliac disease, and those with a history of gastric bypass for weight loss, strict dieting, anorexia, or bulimia

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doi: Cushman CJ, Ibrahim AF, Smith AD, Hernandez EJ, MacKay B, Zumwalt M
Clinical Trial Dosing Range tested: Doses from 0.3 mg up to 4.5 mg weekly have been investigated