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Purity was assessed by flow cytometry on a BD LSRFortessa using anti-CD4 (RPA-T4, 1:400) antibodies and anti-CD8 (RPA-T8, 1:400) antibodies

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Since the CTN Scheme does not require the TGA to review the trial in detail, the timeline primarily depends on how quickly the ethics and institutional approvals are completed

Notably, the low dose of 1D228 at 2 mg/kg already achieved same inhibition rate of Tepotinib at 8 mg/kg (TGI, 1D228-2mg/kg/d:74.4%

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Dermatologists Expertise : A treatment performed by an MD dermatologist ensures higher safety and better outcomes, which can affect the cost