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Whilst it is generally deemed a genetic condition in dogs (specific to certain breeds), in human studies, low levels of B12 have been associated with the condition

Important caveat: This study used a combination product (5-ALA + GHK), not pure GHK-Cu

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These changes were accompanied by shifts in the microbiota composition and microbial activity [276]

Injectable forms were made and worked a little bit, but not satisfactorily