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At the transcriptional level in kidney tubular epithelial cells, glutamine supplementation can downregulate proapoptotic genes (Harakiri [HRK] and BAD) and regulate cytoprotective genes (sulfiredoxin 1 [SRXN1] and heme oxygenase 1 [HMOX1])

[DOI] [PMC free article] [PubMed] 199.Mateen S, Rehman MT, Shahzad S, Naeem SS, Faizy AF, Khan AQ, Khan MS, Husain FM, Moin S

A comprehensive review on this subject by Pferschy-Wenzig and Bauer [224] highlights the many issues that can be underappreciated by consumers who self-medicate on the basis of limited safety and efficacy data

pubmed.ncbi.nlm.nih.gov/30050888 Thomson RL, Spedding S, Buckley JD

Triantafillidis JK, Merikas E, Georgopoulos F (2011) Current and emerging drugs for the treatment of inflammatory bowel disease

COVID-19, a graphic account