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doi: 10.1007/s44274-024-00033-5 185

The R5421 decreased the EV number, size, and RNA content, while the mother cells PS exposure on the cell membrane also decreased due to the inhibition of the scramblase

It exerts hypoglycemic, hypolipidemic and antioxidant effects, inhibits intestinal glucose uptake, increases glucose tolerance and insulin resistance, and stimulates -cell regeneration [64]

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The study involved 5 volunteers aged 50 to 80 years, diagnosed with PD for more than 5 years and with a Hoehn and Yahr grade of 3 or higher