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This may limit the therapeutic potential of ADI as an arginine depleting agent for cancer treatment

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Microglia and a functional type I IFN pathway are required to counter HSV-1-driven brain lateral ventricle enlargement and encephalitis

Selank has the most human data, from a 62-patient trial that found anti-asthenic effects alongside anxiolytic action (Zozulya et al., 2008)

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