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To cope with increased levels of oxidative stress, cancer cells exhibit increased synthesis of antioxidant enzymes responsible for lipid synthesis, which serve as substrates for the lipid peroxidation process

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The metabolic pathway of glutaminolysis becomes essential under hypoxic conditions as it provides necessary energy and maintains metabolic intermediates through glutamine metabolism

GI perfusion Gastrointestinal perfusion is vital for delivery of oxygen and nutrients and removal of toxic metabolic byproducts from the gut mucosa

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Berberine repairs intestinal permeability, stabilizes blood sugar, and neutralizes the bacterial toxin LPS ( 8 )