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Future studies of modafinil as a cognitive enhancer should examine this possibility, and establish whether the drug shows an age- and dose-dependent profile of effects like the classic psychostimulants

Thus, we postulate that pyridoxine is a relatively safe candidate for PD therapy

This helps unclog pores, restricts acne breakouts and reduces oil production while maintaining skin suppleness

The first injection in port A contained the substrate for each individual respiratory chain complex (I: 5 mM pyruvate + 2.5 mM malate, II: 10 mM succinate + 1 M rotenone, III: 0.5 mM duroquinol, IV: 0.5 mM TMPD + 2 mM ascorbic acid) along with 1 mM ADP and 10 nM recombinant perfringolysin O (Agilent Technologies)

2026;4:1010132 DOI: Received: July 20, 2025 Accepted: March 18, 2026 Published: April 13, 2026 Academic Editor: Amnart Poapolathep, Kasetsart University, Thailand The article belongs to the special issue Neuroprotective Potential of Natural Products from Foods Aim: This study evaluated the comparative effects of commonly consumed artificial and natural sweeteners on cognitive function, neurotransmitter-related enzyme activities, and oxidative stress status in the brains of Wistar rats to elucidate their potential neurotoxic or neuroprotective properties under sub-chronic dietary exposure

Pathway enrichment analyses of the upregulated genes against MSigDB Hallmark 2020 database were performed via Enrichr