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In the aspect of HDAC2, there is also consistency showing that repeated electroconvulsive seizures treatment causes the up-regulation of HDAC2 expression both at the mRNA and protein levels in the rat frontal cortex, which further reduces the histone acetylation of H3 and H4 proteins and diminishes NMDA receptor-related genes involved in the development of epilepsy [103]

Correlations between individual ratings of fatigue, clinical scores, length of time of illness, and levels of neurochemicals in pgACC and dACC were carried out using Pearsons product moment and were not corrected for multiple comparisons

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BIBW 2948 is the inhibitor of EGFR, and inhalation of BIBW 2948 (4-week treatment) reduced internalisation of EGFR but did not reduce mucin stores

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J Clin Invest (2021) 131(4):e140100