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Consistent with the PAMPA measurements, the 1,8-diMQ analogue exhibited very low bi-directional transport in the Caco-2 cell assay (Table 2)

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BPC-157 landed in the most contested one: biologically interesting, heavily studied in animals, and almost entirely untested in humans

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Cells involved in repair (fibroblasts, endothelial cells, muscle cells) appear to respond through signaling changes that support migration, collagen organization, and local tissue rebuilding