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The evolving discipline of molecular pathological epidemiology (MPE) offers a powerful approach to explain the interpersonal susceptibility to carcinogenesis and to clarify the role of microbial variation and dysbiosis in the development and progression of tumour anatomical sub-sites within the colorectum and by tumour molecular sub-type features (e.g., inherited MMR mutations, somatic mutations such as in the KRAS , APC , BRAF and PIK3CA genes, microsatellite instability, epigenetic modifications) (62)

Future trends are likely to include technological innovations within the field of IV infusions, high healthcare spending, increased consumer health awareness, and wider applications for therapeutics and cosmetics

10.1042/bj3240041 Biochem

Sig Transduct Target Ther 9 , 316 (2024)

PMID: 32302844 Stem Cell Res Ther Hepatocyte-like cells derived from human induced pluripotent stem cells using small molecules: implications of a transcriptomic study