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Glutathione peroxidase 2 is an intestinal and extracellular enzyme, while glutathione peroxidase 3 is extracellular, especially abundant in plasma

In line, lipid ROS accumulated in Gclc -deficient cells at steady state (Supplementary Fig

According to an analysis of the redox balance, sera antioxidant levels were lower in thyroid cancer patients than in healthy controls, and OxS marker sera levels in thyroid cancer patients were significantly higher than in the control samples (119)

MGMT promoter methylation is associated with temozolomide response and prolonged progression-free survival in disseminated cutaneous melanoma

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This was in complete contrast to the properties of Beppu's anti-band 3 antibodies, for which these authors showed an 80% inhibition of binding to oxidatively stressed RBC by 10 g/ml lactoferrin (Beppu et al., The second round of studying anti-band 3 specificity confirmed the initial characterization of anti-band 3 NAb preparations of Lutz and suggested that Beppu's group must have used a different type of starting material that upon purification on immobilized band 3 protein yielded anti-N-acetyllactosaminyl-specific IgG and anti-band 3 NAbs