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Description
The scores of compounds were used to guide the medicinal chemistry optimization of DEL7

Reductions in GABA levels found in patients with ALS in motor cortex compared to healthy controls (Foerster et al., 2011)
This condition can irritate or compress the spinal nerve roots, resulting in low back pain (172, 173)

Cyanobacteria, which appeared ca 200 million years before the GOE, were the inductors of this phenomenon, because cyanobacterial photosynthesis resulted in the accumulation of free oxygen in the atmosphere

Naiel et al., 2023)

we discuss this at consultation
