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Therefore, the commensal microbiota is often regarded as a hidden organ. Commensal microbiota-derived metabolites have substantial impacts on host physiological functions through metabolic reprograming (64), epigenetic modifications (65), and the activation of specific receptors like G protein-coupled receptors (GPRs) and aryl hydrocarbon receptor (AhR)

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10.3389/fphar.2019.01104 103 NunesC.AlmeidaL.BarbosaR

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Clinical spectrum and genetic variation of six patients with methylmalonic aciduria (MMA)
